Drug Sensitivity

diffdock is a docking skill for predicting protein-ligand binding poses from PDB structures or protein sequences plus ligands in SMILES, SDF, or MOL2. Use the diffdock skill for structure-based drug design, virtual screening, and confidence-scored pose analysis. It is not for binding affinity prediction.

depmap helps analyze the Cancer Dependency Map for cancer cell line gene dependency scores, drug sensitivity, and gene effect profiles. Use it to identify cancer-specific vulnerabilities, synthetic lethal interactions, and validate oncology drug targets with a reproducible depmap guide for Data Analysis.