Opentrons

opentrons-integration helps write Opentrons Protocol API v2 Python protocols for OT-2 and Flex robots. Use it for production liquid handling, deck layout, module control, serial dilutions, PCR setup, and backend-style automation. It is best when you need a reliable opentrons-integration guide for exact protocol scripting, not multi-vendor orchestration.

pylabrobot is a hardware-agnostic Python framework for lab automation. Use the pylabrobot skill to control liquid handlers, plate readers, pumps, incubators, and centrifuges, manage deck layouts, and simulate protocols before execution. Good for multi-vendor workflows and reproducible automation.